Paper Title
Differential Profile Rrotein Rattus Norvegicus Type 2 Diabetes Mellitus (T2DM) Model

Abstract
Type 2 diabetes mellitus (T2DM) caused by resistance insulin. Resistance insulin leads to hyperglicaemia. Prolong hyperglicaemia caused demage organ and complication such as nephropati (kidney), liver and cardio vascular diseases.Mean while hyperglicaemia inhibits protein metabolism. This study focused to investigated of profile protein organ kidney, liver and heart in T2DM rat animal model. This research was used rats group T2DM (DM) and normal rats as a control (C). We isolated Protein from tissues and SDS-Page to investigated profil protein. This result we found has different profile protein in T2DM rats (DM) compared with control rats (C). Several protein has absen in T2DM conditian and several protein has found in T2DM condition, meanwhile in control rats we found several protein different T2DM rats goup. This study concluded has different profile protein in rats group T2DM (DM) and rats control group (C). Keywords: Hyperglicaemia, SDS-PAGE, T2DM