Paper Title
Caracterization of Curcuminoid Nanoemulsion and Its Biological Activity Test

Abstract
Curcuminoid is the main compound found in the Curcuma xantorrhiza rhizome. C. xantorrhiza plant which in Indonesia is known as temulawak is an herbal plant that is traditionally used to cure hepatitis, increase stamina, and as an anti-cholesterol. To enhance the stability, solubility and activity of the curcuminoid, should be developed into a product nanoemulsion. This work reports the synthesis and characterization of curcuminoid nanoemulsionproduced by spontaneous nanoemulsion method. Curcuminoid nanoemulsion was madeby the addition of surfactants, oils, and phosphate buffer pH 7.0 in various variations of the composition.Nanoemulsion characterization was carried out using particle size, zeta potential, and stability. The antioxidant activity test was carried out using the DPPH method. Antibacterial activity was tested using Kirby-Bauer disc diffusion method on pathogenic bacteria. The curcuminoid nanoemulsion obtained had a particle size <50 nm; polydispersity index (PI) <0.6; and zeta potential of -1.8 to -11.1 mV. Curcuminoid nanomulsion obtained is water soluble, has high antioxidant activity, and inhibits the growth of pathogenic bacteria. Keywords – Antioxidant, Antibacterial, Curcuma Xanthorrhiza, Curcuminoid Nanoemulsion.